Plant hormones are chemicals that are present in small amounts, influence and promote the division, growth, and maturation of cells and tissues. Salicylic acid is a phenolic phytohormone and has a function in growth/development, photosynthesis, transpiration, ion absorption, and transport. By interfering with endogenous signals, SA mediates plant defense against pathogens. It strengthens the body's defenses against infections by promoting the production of pathogenesis-related proteins. It affects the systemic acquired resistance (SAR) pathway, wherein a pathogenic assault on one. Water deficiency affects during tillering, head emergence, filling of grain and maturity water deficiency of wheat. Concentration of carotenoids more during drought stress and that produced for drought tolerance enhancement in bread wheat. Water shortage on pigment contents of photosynthesis, relative water amount, shot weight in dried form, flag leaf area specific mass, parameters for gas exchange, physiological parameters and yield. Drought there more significant reduction in tillers/plant, fertile tillers/plant, length of spike, yield/spike and thousand kernel weight of wheat cultivars during drought conditions as compared with normal irrigation conditions. Polyamine exogenously via spray during grain filling condition. The water deficiency spermidine and spermine reduced the inhibition caused by water deficiency when polyamine had applied.