Xây dựng giá trị tham chiếu các chỉ số xét nghiệm Sinh hóa tại Trung tâm Xét nghiệm, Trường Đại học Y tế công cộng

Abstract

Objective: Establish biochemistry reference intervals suitable for the Laboratory center of Hanoi University of Public Health. Methods: The study was carried out based on guidance of CLSI EP28-A3 using indirect sampling method. 8345 normal sample from January 2018 to April 2021 in Laboratory center of Hanoi University of Public Health is used. Results: The results showed that the biochemistry reference intervals was established as below: GLU (3.94-6.38 mmol/L), men (3.94-6.48 mmol/L), women (3.95-6.26mmol/L); CHOL (3.46- 6.06 mmol/L), male (3.55-6.10 mmol/L), female (3.44-6.02 mmol/L); TRI (0.46-2.20 mmol/L), male (0.56-2.24 mmol/L), female (0.44-2.11 mmol/L); URE (2.62-7.10 mmol/L), men (2.93-7.32mmol/L), women (2.48-6.72mmol/L); CRE (53.62-107.09 µmol/L), men (68.58-111.14 µmol/L ), women (50.35-86.54 mol/L); AST (13.46-32.27 U/L, men (14.05- 32.83U/L), female (13.03-30.99 U/L); ALT (7.21-34.14 U/L), men (7,91-35,06 U/L), female (13,03-30,99 U/L). Conclusions: The reference intervals determined in our research have the significant differences to the reference intervals currently used in our laboratory. Key words: Reference interval, Laboratory Center, Hanoi University of Public Health