Abstract
When the limited pelvic lymph node dissection in prostate cancer patients can be justified?
Highlights
When the limited pelvic lymph node dissection in prostate cancer patients can be justified? Molchanov R.M., Stakhovskyi E.O., Kriachkova L.V., Pilin Ye.V., Malinovskyi S.L
According to ROC analysis, the diagnostic efficacy of limited pelvic lymph node dissection (PLND) increases in patients at high and moderate risk at a total prostate specific antigen (PSA) level greater than 18.4 ng/ml. This can be used to justify the indications for limited PLND in patients in these groups to reduce the number of postoperative complications associated with extended procedure
We found no statistically significant differences in the number of complications of PLND in open and laparoscopic surgery (p=0.16), the overall frequency of which was 22.8%
Summary
When the limited pelvic lymph node dissection in prostate cancer patients can be justified? Molchanov R.M., Stakhovskyi E.O., Kriachkova L.V., Pilin Ye.V., Malinovskyi S.L. Extended pelvic lymph node dissection (PLND) is an important diagnostic step in the surgical treatment of moderate and high risk prostate cancer (PCa) according to D'Amico criteria It has a number of complications and prolonged time of surgery. According to ROC analysis, the diagnostic efficacy of limited PLND increases in patients at high and moderate risk at a total PSA level greater than 18.4 ng/ml. This can be used to justify the indications for limited PLND in patients in these groups to reduce the number of postoperative complications associated with extended procedure. За даними ROC-аналізу, діагностична ефективність обмеженої лімфаденектомії зростає у хворих груп високого і помірного ризику при рівні загального ПСА більше 18,4 нг/мл. The main treatment for localized PCa is radical prostatectomy, which provides high rates of overall and relapse-free survival with relatively low complications [10]
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