Abstract
Hamster embryo cells abortively infected with human adenovirus type 12 synthesized only a small amount of virus-specific RNA up to 30 hr after infection. Some of the characteristics of the viral RNA were compared with those of “early” viral RNA from infected KB cells. It was found that (i) they had the same average guanine plus cytosine content as estimated by melting profiles of DNA-RNA hybrids, (ii) they had similar size distribution and (iii) they contained very similar nucleotide sequences as determined by competition-hybridization experiments.
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