Abstract

The paper shows the results of electrophysiological methods of investigation in patients with multiple sclerosis (MS) in the aspect of comorbidity. The studies of somatosensory evoked potentials (SSEP) in 216 patients with MS and electroneuromyography in 158 patients with MS, together with the assessment of neurological and psychological status. It is shown that according SSEP increase latency peripheral response in a progressive course of MS compared to remitting associated with older age of patients with progressive MS, and due to involvement in the pathological process of the peripheral nervous system (PNS) and the prevalence of pain syndrome (PS) in patients MS with comorbidity. It is demonstrated, on the basis of electroneuromyographic that MS patients with comorbidity tends to be deeper shock PNS. The data electroneuromyographic clinically appropriate initial stage of sensory or sensorimotor polyneuropathy, which proceeded in 84.8% of patients with MS subclinical and 15.2% had a clear clinical signs.

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