Abstract
The purpose of the study is to validate ThyPRO-39 questionnaire to Brazilian Portuguese. The validated Portugal Portuguese version of ThyPRO-39, provided by the questionnaire developer, was used to adapt it to Brazilian Portuguese and these changes were validated by a translator. A cross-sectional study was carried out on people with thyroid disease, who were invited to participate in the research through the study author's social media. The study occurred between August 2020 and October 2020 and included 516 participants. Results obtained in both questionnaires, SF-36 and ThyPRO-39br, showed moderate correlation in all similar scales, Cronbach's alpha was higher than 0.7 in 10 of the 12 scales, and the clinical validation showed that results obtained were compatible with the expected for the patient diagnosis. Regarding the convergent validation between the ThyPro-39br and SF-36 questionnaires, the strongest correlations were found between the final composite score of ThyPRO-39br and SF-36 functional capacity (-0.591, p<0.001), impact on daily life and physical aspects (-0.568, p<0.001), and anxiety and mental health (-0.541, p<0.001). The ThyPRO-39br version was satisfactorily validated through 3 different methods and is available for future thyroid diseases quality of life research in Brazil.
Published Version
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