Abstract
UWT/OC07 - Effect of non-adhering dressings on promotion of fibroblast proliferation and wound healing in vitro
Highlights
Non-adhering dressings are commonly used during granulation, tissue formation, and reepithelialization
Any dressing that is applied to a wound comes into intimate contact with cells involved in the healing process
Fibroblasts are the key cells in the production of extracellular matrix that is required to fill the wound with newly synthesized tissue[10]
Summary
Non-adhering dressings are commonly used during granulation, tissue formation, and reepithelialization. Silicone AT, polyester + gly and polyamide + vas + CMC caused distinct cell damage The latter two further reduced cell viability, proliferation and scratch healing. Several comparative clinical studies have been performed including non-adherent dressings such as Melolin[4], paraffinated gauze[3], Urgotul[5,6], Atrauman[7], Mepitel[8] and others These trials focused on safety and efficacy as well as reduction of wound pain and tissue trauma during dressing removal. Fibroblasts are the key cells in the production of extracellular matrix that is required to fill the wound with newly synthesized tissue[10] Upon tissue injury, they start to migrate into the damaged site and deposit collagen[1]. Description cotton + vas Lomatuell H, Lohmann & Rauscher cotton tulle with a vaseline coating polyester + TLC
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