Abstract
Introduction: Antimicrobials are readily prescribed to seriously ill patients, accounting for a large portionof the drugs administered in intensive care units (ICU). Objective: Aimed to explore the antibiotic usagepatterns in the ICU patients of a tertiary care hospital, Sylhet MAG Osmani Medical College Hospital.Methods: A hospital-based retrospective observational study was conducted to explore the pattern of usageof antibiotics in the ICU of Sylhet MAG Osmani Medical College Hospital. The medical records of 530patients admitted to the ICU from July 2020 to June 2021 were reviewed. Results: Antibiotic treatmentwas given to 94.0% of the ICU patients. A culture sensitivity test was done in 72.1% of patients; bloodsamples were more frequently cultured (42.0%). 412 (95.2%) of the 433 samples showed a positive cultureresult. Klebsiella made up 33.3% of the isolated organism. The mean amount of antimicrobials given perpatient was 2.5±1.4. Cephalosporin (38.8%), Carbapenem (31.3%), and Penicillin (29.0%) were the mostcommonly given antimicrobial groups. About half of the patients (50.8%) received multiple antibiotics.The most frequently used drug combinations were Ceftriaxone and Metronidazole, which were given to48.0% of the patients. Conclusion: Cephalosporin and Carbapenem were most frequently utilized asantibacterial agents in this ICU. However, due to the rise of resistance, physicians should be moreaware of using these drugs.
Published Version
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