Abstract
Abstract Introduction: Calcium hydroxide (Ca(OH)2) is the most commonly used medicament in endodontics. This study aimed to investigate the effect of bioactive glass (BG) use with or without Ca(OH)2 on the biological and mechanical properties of dentin. Materials and Methods: Standard holes were created to simulate root canals on 84 dentin slices. Four groups were formed according to the medicament placed in the root canals: Ca(OH)2; Ca(OH)2 + 7% BG; BG and control. Scanning electron microscopy analysis to evaluate the dentin surfaces exposed to the test medicaments and energy dispersive X-ray analysis to observe apatite formation were used on the 1st, 7th, and 14th days. X-ray diffraction measurements were performed to investigate mineral phase formation. Microhardness and pH measurements were also carried out. Data were analyzed using Kruskal–Wallis and Wilcoxon signed-rank tests (P < 0.05). Results: The Ca(OH)2 and control groups showed the highest Ca and P mineral content on the 14th day, whereas the lowest Ca and P content was found in the Ca(OH)2 + BG group (P < 0.05). A gradual decrease in crystal formation was found in the Ca(OH)2 + BG group from the 1st day to the 14th day. The highest microhardness measurements were also recorded in the Ca(OH)2 + BG group (P < 0.05). The Ca(OH)2 + BG group showed the highest pH measurements (P = 0.001). Conclusions: Ca(OH)2 + BG can be an alternative intracanal medicament. Further studies should be performed to determine the clinical implications of this combination.
Published Version
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