Abstract
Hypoxia during pregnancy poses intricate challenges to both maternal and fetal well-being, demanding a nuanced exploration of its various dimensions. This comprehensive review consolidates the current state of knowledge on hypoxia in pregnancy, encompassing its forms, underlying mechanisms, implications, diagnostic approaches, management strategies, and global perspectives. The review highlights the multifaceted nature of hypoxia, incorporating insights into chronic and intermittent hypoxia, molecular and physiological mechanisms, potential complications, diagnostic tools, and management interventions. Furthermore, it addresses the lasting impact of maternal hypoxia on offspring development, emphasizing neurodevelopmental outcomes, cardiovascular health, and the risk of chronic diseases. The global perspective section underscores the importance of understanding regional disparities, socioeconomic factors, and healthcare access in addressing hypoxia during pregnancy on a global scale. The review concludes by identifying research gaps and advocating for multidisciplinary collaborations and innovative research approaches to advance our comprehension of hypoxia’s complexities in pregnancy. Ultimately, this comprehensive overview aims to contribute to the enhancement of maternal-fetal healthcare by providing a holistic understanding of hypoxia in pregnancy
Published Version
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