Abstract

Pleomorphic lobular carcinoma in situ represents as an exceptionally discerned, morphological subtype of lobular carcinoma in situ (LCIS). Neoplasm is contemplated to express a genetic and biological advancement of classic lobular carcinoma in situ and emerges as a direct precursor to invasive carcinoma breast. Initially scripted by Frost et al in 1996, pleomorphic lobular carcinoma in situ is contemplated as a morphologic variant of classic lobular carcinoma in situ.

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