Abstract
Thymine-containing pyrimidine dimers have been isolated and identified chromatographically from DNA hydrolysates of ultraviolet-irradiated Tetrahymena. Removal of these photoproducts has been observed during post-irradiation growth of cells in the dark. After 47 h, about 83 % of the pyrimidine dimers disappear from the trichloroacetic acid-insoluble fraction. Further analysis of both the trichloroacetic acid-insoluble and trichloroacetic acid-soluble fractions indicated that photoproducts accumulating in the soluble fraction are eventually lost from the cytoplasm of irradiated cells.
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