Abstract
In this work we show an optical fiber evanescent wave absorption probe for glucose detection in different physiological media. High selectivity is achieved by functionalizing the surface of an only-core poly(methyl methacrylate) (PMMA) polymer optical fiber with phenilboronic groups, and enhanced sensitivity by using a U-shaped geometry. Employing a supercontinuum light source and a high-resolution spectrometer, absorption measurements are performed in the broadband visible light spectrum. Experimental results suggest the feasibility of such a fiber probe as a low-cost and selective glucose detector.
Highlights
The attention of the scientific community has been focused on low-cost, sensitive, and specific alternatives for the detection and analysis in low concentration solutions of different substances due to the demand in many fields such as clinical diagnosis, drug discovery, food safety, etc., [1]
The functionalization process carried out this requires work requires an exhaustive of the modification at each step
We have reported a potential glucose detection platform
Summary
The attention of the scientific community has been focused on low-cost, sensitive, and specific alternatives for the detection and analysis in low concentration solutions of different substances due to the demand in many fields such as clinical diagnosis, drug discovery, food safety, etc., [1] In this sense, glucose sensing and monitoring is regarded as a critical indicator, so that fabricating reliable solutions would result in a step forward [2]. The use of polymer optical fibers (POF) fulfils perfectly the requirements of biosensors and provides many advantages in comparison to other types of sensors, mainly owing to the high interaction lengths with the sample and the transmitted light as well as the simplicity of the sensors [5].
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