Abstract
Regenerative injection therapy (RIT), also known as prolotherapy or sclerotherapy, is a treatment for chronic musculoskeletal pain caused by connective tissue diathesis utilizing chemical or biologic substances. Steroidal and nonsteroidal anti-inflammatory medications are useful in degenerative disease processes with concomitant inflammatory changes or fibrosis which tethers adjacent structures such as nerves or tendons. In such instances, hydrodissection with injectates containing corticosteroid may also prove useful. RIT is a viable, type-specific treatment for chronic conditions that involve collagen destruction or degeneration. Multiple controlled and uncontrolled studies indicated effectiveness of RIT in treating painful degenerative musculoskeletal conditions.
Published Version
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