Abstract
Introduction. Normalization of menstrual function in adolescent girls is a prevention of reproductive health disorders in the future, which determines the need for new methods of therapy.Aim of the study. To normalize the menstrual cycle and reduce body weight in adolescent girls with menstrual dysfunction andobesity of various degrees by developing an eff ective and advanced treatment complex.Materials and methods. Two groups were formed: the control group – 31 healthy teenage girls and the main group – 79 teenage girls with menstrual disorders and obesity, divided into two subgroups: I – 44, who received the treatment developed by us, II – 35, who received the traditional, generally accepted therapy.Research methods: general clinical, gynecological, ultrasound. Statistical analysis according to generally accepted methods of variational statistics. Approval of the scientifi c work was obtained from the Bioethics Committee of the Bukovyna State Medical University (Ukraine). The work is a fragment of the research work «Prevention, diagnostics and treatment of disorders of perinatal period and reproductive system of women and adolescent girls» (201110Н, state registration number 0111U006499).Research results. The proposed treatment leads to a signifi cant decrease in body mass index regardless of the degree of obesity, glucose in the second degree from 4.86 ± 0.43 mmol/l to 4.65 ± 1.1 mmol/l (р ˂ 0.05) and in the third degree from 5. 81 ± 0.12 mmol/l to 4.93 ± 0.7 mmol/l (р ˂ 0.05), establishing a regular menstrual cycle in 90.3% with oligomenorrhea for less than two years and 79.3% for more than two years, with traditional therapy – 78.0%, 58.9% (р ˂ 0.05).Conclusions. The improved treatment complex leads to normalization of the menstrual cycle in 90.3%, reduction of body weightand prevention of polycystic ovary syndrome.
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