Abstract

The injection of different doses of allogeneic adult blood leucocytes intraperitoneally into Xenopus laevis larvae at various stages of development failed to induce tolerance either in splenic mixed lymphocyte reactions or in skin graft rejection responses when the hosts were tested against their donors as 2–6 month old toadlets. The results are discussed in relation to the various methods used for the induction of transplantation tolerance.

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