Abstract
This chapter presents an introduction to the symposium on immune responses of gut-associated lymphoepithelial tissue (GALT). It is much less common for antigen to be introduced into the body by subcutaneous, intravenous, or intraperitoneal routes than it is for antigen to enter through the gut epithelium. There is a constant supply of antigen in the gut lumen, consisting of portions of ingested food materials and of microorganisms and their byproducts. As with other questions of broad biological application, clarification of the nature of GALT must include (1) careful observation and comparison of phylogenetic variations that may represent alternate solutions to one general problem and (2) a detailed look at development of structure and function within the individual.
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