Abstract
Herein, the construction of 3-indolemalononitriles via base-promoted tandem decarboxylative propargylation/aromatization cascade of 4-ethynyl benzoxazinones with N,N-disubstituted aminomalononitriles has been developed. This protocol features mild reaction conditions, high efficiency and no need of transition metals. Various 3-indolemalononitriles can be obtained in moderate to excellent yields from readily available starting materials. More importantly, this method can be further applied to the synthesis of a wide range of complex indole products.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
