Transcranial direct current stimulation on the clinical curative effect of patients with disturbance of consciousness

Abstract

Transcranial direct current stimulation (Transcranial direct current stimulation, tDCS) is a non-invasive brain stimulation technique. tDCS plays a role by regulating the activity of spontaneous neuronal networks. Such as stimulation in patients with primary cerebral cortex motor area (M1), which can effectively improve the patient's motor dysfunction, and stimulate the prefrontal cortex, which can effectively improve patient swallowing dysfunction, etc. but the tDCS with conventional rehabilitation therapy in patients with disturbance of consciousness of clinical research is rarely reported. To explore the clinical efficacy of transcranial direct current stimulation on the clinical curative effect of patients with disturbance of consciousness(DOC). Thirty-eight DOC patients were randomly divided into a observation group and a control group, each of 19. Both groups were given routine rehabilitation intervention, and the observation group were treated with transcranial direct current stimulation on this basis for 20 sessions. The Brainstem auditory evoked potential (BAEP), the Upper sense evoked potential (USEP), the nerve electrophysiology evaluate electroencephalogram (EEG) and the Glasgow coma scale (GCS) or PVS rating scale were used to test both groups before and after the treatment. Before treatment, the two groups of patients were compared with BAEP, USEP, EEG, GCS or PVS scores, and the difference was not statistically significant ( P > 0.05). After treatment, BAEP, USEP, EEG, GCS or PVS scores were compared with those in the group before treatment, and the difference was statistically significant ( P < 0.05). And the observation group's BAEP, USEP, EEG, GCS or PVS scores were better than the control group ( P < 0.05). On the basis of conventional rehabilitation therapy, tDCS treatment can further improve the patients’ consciousness disorder, and this combination therapy is worthy of clinical promotion and application.