Effects of hyperbaric oxygen on brainstem auditory evoked potential and somatic evoked potential of patients with moderate and severe traumatic brain injury and analysis of its therapeutic efficiency

Abstract

Objective To investigate effects of hyperbaric oxygen (HBO) on brainstem auditory evoked potential (BAEP) and somatic evoked potential (SEP)of patients with moderate and severe trauma tic brain injury and to analyze its therapeutic efficiency. Methods One hundred and thirty-four patients with moderate and severe trauma brain injury were randomly divided into the control group (67 cases) and the HBO adjunctive therapy group (HBO group, 67 cases). The control group received essential neurosurgical treatment and conventional drug treatment, and the HBO group was given HBO therapy for three sessions in addition to the same treatment received by the control group. BAEP and SEP were detected and the scores of Glasgow coma scale (GCS) were measured before and after treatment. Glasgow outcome scale (GOS) were evaluated in follow - ups 6 months after injury. Results Abnormality of BAEP, SEP and GCS for the patients of both groups showed no statistical difference before treatment (P > 0.05). After treatment, significant improvement could be seen in BAEP of the control group(P <0. 05), and more significant improvement was noted in SEP (P <0.01), GCS also increased significantly in the control group (P <0.05). For the HBO group, BAEP and SEP all improved Key words: Hyperbaric oxygen;  Traumatic brain injury;  Brainstem auditory evoked potential;  Somaticevoked potential;  Glasgow coma scale;  Glasgow outcome scale