Abstract
The basis for absorptive trace element interactions is given by the statement of Hill & Matrone (1970) that “those elements whose physical and chemical properties are similar will act antagonistically to each other biologically”. Although the direct antagonistic competition of chemically-alike metals is a straightforward concept, an important associated view is that dietary preconditioning with an excess or deficiency of an element may reveal interactions with the metabolism of chemically-similar metals.
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