Abstract
Medicinal plants are highly investigated due to their multiple effects in human health. In the last two decades, plants belonging to Lamiaceae family have emerged as an important source of compounds with beneficial effects in various pathologies. Many species of the Lamiaceae family have a high volatile oil content which can be found in different parts of the plant. Some representative examples include Lavandula spp. Salvia spp. and Mentha spp. which are species with essential oils studied for antioxidant, antimicrobial and antitumor effects. The aim of this study was to evaluate the effect of six essential oils at skin level before and after encapsulation in hydroxypropyl-gamma-cyclodextrins. Results indicated that regardless of the tested form, the samples did not display an irritating or toxic effect at skin level, suggesting that the essential oils can be used in different formulations for topical application.
Highlights
Medicinal plants are highly investigated due to their multiple effects in human health
According to Cavanagh et al, lavender essential oils (EO) is used in numerous dermatological conditions such as dermatitis, eczema and psoriasis, but they pointed that there are studies showing that exposure to lavender oil can produce dermatitis [6]
Lavandula angustifolia Mill. - was collected from Timisoara Young Naturalists Resort; Salvia officinalis L. -collected from Madrid experimental field, Spain; Lavandula hybrida Balb. ex Ging - collected from Timisoara Young Naturalists Resort; Salvia sclarea L. - collected from Timisoara Young Naturalists Resort; Mentha smithiana L. - collected from Timisoara Young Naturalists Resort; Mentha piperita L. - collected from Timisoara Young Naturalists Resort
Summary
Medicinal plants are highly investigated due to their multiple effects in human health. The present study was aimed to provide a toxicological evaluation of some essential oils obtained from Lavandula spp. Salvia spp. and Mentha spp, belonging to the Lamiaceae family and harvested from Romania and to establish their effects at skin level after encapsulation in hydroxypropyl-gamma-cyclodextrins.
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