Toxicity and Total Phenolic Content of Saurauia vulcani Extracts from Cultivation

Abstract

Saurauia vulcanii plant has been widely used to treat a variety of diseases suffered by villagers as antidiabetic and digestive problems’ remedy. The Forestry Research and Development Agency has cultivated this plant at Forest Area for Specific Purpose in Northern Sumatra. The aims of this study were to determine the toxicity and total phenolic content from n-hexane, ethyl acetate and methanol Saurauia vulcani extracts. The toxicity was carried out using the Brine Shrimp Lethality Test (BSLT) method and Folin Ciocalteu method is used for total phenolic content. The result showed that the toxicity of n-hexane, ethyl acetate and methanol extracts i.e. LC50 values of 365.19 ppm, 715.28 and 225.77 ppm, respectively. The total phenolic content of hexane, ethyl acetate and methanol extracts were 7,155 mg GAE/g, 13,702 mg GAE/g and 16,560 mg GAE/g, respectively.