Abstract
To evaluate the accuracy and repeatability of the Tono-Pen XL™, TonoVet® and TonoVet Plus® tonometers by manometric evaluation, and to establish adjustment equations for intraocular pressure (IOP) estimates in rabbits. Rabbits. A postmortem study was conducted on seven rabbit eyes to verify the correlation between manometry and tonometry with an artificial incremental increase in IOP from 5 and 60mmHg. A clinical study was conducted to evaluate accuracy and to establish reference values for the species, with measurement of IOP in 17 animals, for 2 consecutive days, with the same tonometers and calibrations used in the postmortem evaluations. There were strong linear trends for all evaluated tonometers. In the in-vivo evaluation, the mean IOP values were: 14.23±1.75 (Tono-Pen XL™); 13.89±2.07 (TonoVet® calibration mode 'd'); 8.88±1.24 (TonoVet calibration mode 'p'); 18.59±1.94 (Tonovet Plus®). There was a significant difference in the two evaluation times for the two TonoVet® calibration modes. The adjustment equations generated from the manometry for the evaluated tonometers were: Y=0.2570X+2.219 (Tono-Pen XL™), Y=0.2289X+2.389 (TonoVet® 'd'), Y=0.4043X+4.062 (TonoVet® 'p'), Y=0.1233X+0.3644 (TonoVet Plus®) (X is device-estimated IOP). All evaluated tonometers were well correlated with the manometry, with an underestimation of IOP by all devices. Applying adjustment formulas may compensate for systematic errors. TonoVet Plus® was well tolerated, and showed better repeatability and reliability in successive evaluations.
Published Version
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