Tobacco smoke is not limited to second hand smoke.

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We read with interest “Thirdhand Smoke Exposure Induces Oxidative Damage, Initiates Skin Inflammatory Disease, and Adversely Alters the Human Plasma Proteome” by Sakamaki-Ching et al.,1 which is reported by the authors as the first clinical study identifying the molecular adverse health effects of third-hand smoke (THS) dermal exposure in humans. Tobacco smoke exposure is not limited to Second-Hand smoke (SHS), THS, known as the combination of gases and particles that, after having smoked, persist on surfaces, in dust or even on people's hair, skin and clothing.