Abstract

Objective To evaluate high risk factors contribute to acute respiratory failure ( ARF )in children with novel influenza A ( H1N1 ) virus infection. Methods 51 children( ≤ 14 years old ) with novel influenza A ( H1N1 ) virus infection were enrolled from 2009-9-19 to 2010-1-31. To collect the clinical data and restrospective analysis was used in this study. Results 5 cases complated with respiratory failure. The incidence of respiratory failure in children with novel influenza A ( H1N1 ) virus infection in our hospital is 9.80%. Throught Logistic regression analysis, there are high risk factors insreasing children with novel influenza A ( H1N1 ) virus infection liability to respiratory failure: recent respiratory tract infection or use of immunosuppressive agents; neutrophil cell count > 70%. Conclusions In children with novel influenza A ( H1N1 ) virus infection, respiratory tract infection should be prevented and treated actively in order to prevent respiratory failure. Key words: Novel influenza A ( H1N1 ); Acute respiratory failure ( ARF ); High risk factors; Children

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