Analysis of viral etiology in 618 children with respiratory tract infection

Abstract

Objective To investigate the incidence of the common respiratory viruses in children with respiratory tract infection and to compare the results among different ages and to analyze the relationship between wheezing of children and various viruses. Methods Nasopharyngeal secretions of 618 children with respiratory infection hospitalized were assayed for 7 respiratory viruses, including respiratory syncytial virus, adenovirus, influenza A virus, influenza B virus, parainfluenza virusⅠ、Ⅱ、Ⅲ. Results (1)A total of 166 cases, affected with viral etiology, were detected in 618 samples, and the total positive rate was 26.86%.The most common virus was RSV(17.96%), followed by PIVⅢ(5.99%), IFA(1.62%), ADV(0.81%), PIVⅠ(0.49%). Moreover, 1case infected with RSV and PIVI was included, with the positive rate 0.16%.(2)The positive rates were different in various ages, with 14d~<1-year 35.04%, 1~<3-year 18.25%, 3~<6-year 17.11% and ≥6-year 9.26%.(3)There were differences of positive rate of viruses among different respiratory infectious diseases, and capillary bronchitis occupied the highest percentage(47.37%). (4)Among all the detected children, infants were more likely to whee in auscultation of lung, and RSV was the primary etiology. Conclusion RSV, which was the primary viral etiology in children with wheezing, was the most common virus leading to respiratory infection of children, followed by PIVⅢ.In the children with respiratory tract infection, the viral infection tends to occur in younger children. Key words: Respiratory infection; Etiology; Virus infection; Children