The characteristics of hospitalized children with non mixed infection of bacterial pathogens of acute respiratory tract infection pathogen based

Abstract

Objective To explore the frequency, clinical presentations and impact of coinfections of respiratory agents on hospitalized children. Methods Patients from May 2014 to 2015 March in my courtyard department of Pediatrics inpatient treatment of acute respiratory tract infections in children were taking venous blood 2 ml by indirect immune fluorescence detection 9 kinds of common respiratory pathogens early specific antibody IgM within 24 hours of admission.Statistical analysis on the detection results and clinical data of the pathogens. Results The total positive rate was 51.2% (147/287). The detection rate of each pathogen was the first 30% (86/287) of influenza virus A, followed by influenza virus B was 28.2% (81/287). The pathogen detection rate of 3-6 age group was 56.3% (54/96) and pathogen mixed infection rate was 40.6% (39/96), among which the double infection of influenza virus A combined with influenza virus B was the most common (48.5%; 16/33). According to the month distribution, in August, the highest incidence rate of pathogens, accounting for 80% (12/15). According to the pathogen detection results, there were no significant differences between the three groups in clinical characteristics of fever, cough, disease (upper and lower respiratory tract infections), hospital days and white blood cell count.The positive rate of influenza virus A, influenza virus B and influenza virus 1 in mixed infection was higher than that of single infection (P<0.05). Conclusions There is a higher occurrence of infections with two or more respiratory pathogens in children admitted with acute respiratory infections, and influenza A virus is the most common virus detected in coinfections.While infections with two or more respiratory pathogens don′t cause more-severe clinical illness than infections with a single respiratory agent. Key words: Coinfections; Respiratory tract infection; Pediatrics; Hospitalized; Children