Abstract
Bronchial asthma is a chronic airway allergy disease involving the imbalance of Th1/Th2.Th2 shift is one of the primary causes of asthma.Recent studies have found that T cell immunoglobulin and mucin domain molecule 1(TIM-1) play important roles in T cell activation and Th1/Th2 differentiation in asthma,which has been intensively reported in recent researches.This article reviews the characteristics of TIM-1 gene and its role in the pathogenesis of bronchial asthma.
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