Abstract
Tiamulin is a semi-synthetic derivate of Pleuromuti lin antibiotic; produced by Pleurotus mutilus ; active against mycoplasmas; treponemas; leptospires ; Gram positive and negative germs. The aim of the study was the study of tiamulin resi dues in pork and pig liver in order to establish th e withdrawal period. To accomplish this purpose; it w as developed a study regarding the Tiamulin residue depletion as a consequence of Tiagen 80% product administering in pigs; in a dose of 12 mg / kg / day during 5 days. After the treatment; there were slaughtered 10 anim als in the 1 st ; 3 rd ; 5 th ; 6 th and 7 th day and there were collected samples from muscles and liver. After pro cessing; these samples were analyzed by High Pressure Liquid Chromatography method (HPLC). After these determinations; it was noticed that the best representation of residual depletion in pork and pig liver is the polynomial equation and the Tiamul in concentration is lower than MRL after 6 days in pork and 5 days in liver.
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