Abstract

This paper describes the extraction of embeline from its plant source . The embelin is highly handy in the medical management viz., cytotoxic, antib acterial, wound healing, chemo preventive, lipid lowering agent and many other medical usages. The substituted benzoyl ester derivative of the embelin molecule will also have the medical properties more or less then the parent embelin molecule. They substi tuted derivatives were synthesized by reacting emb elin with different substituted benzoyl h alides in the presence of pyridine as base and dichloro methane as solvent. Amongst them , Fluoro, bromo and Iodo ( halide s) substituted benzoate esters exhibited diffe rent thermal activit ies then its parent embeline molecule . The se substituted benzoyl halides showed different thermal activities . The se properties are varying with respect to the position of halide in the phenyl substituted ring . The thermal prosperities p layed vital role in altering lipid lowering activity of the molecule.

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