Therapeutic effect of the combined treatment of mecobalamin and salvia miltiorrhiza ligustrazine on diabetic peripheral neuropathy

Abstract

Objective To learn therapeutic effect of the combined treatment of mecobalamin and salvia miltiorrhiza ligustrazine on diabetic peripheral neuropathy.To provide effective and reliable operation method for the treatment of disease. Methods 163 cases with diabetic peripheral neuropathy were randomly divided into observation group(86 cases) and control group(77 cases). The observation group was treated with mecobalamin combined salvia miltiorrhiza ligustrazine, the control group was treated with mecobalamin.The sensory conduction velocity (SNCV) and motor conduction velocity (MNCV) were measured in the two groups before and after treatment.The therapeutic effects were evaluated after one course. Results The MNCV and SNCV of the two groups were higher than before treatment, the difference was statistically significant (t=24.298, 25.546, 18.737, 15.733, 14.284, 14.886, 9.337, 9.402, all P 0.05). Conclusion In the treatment of diabetic peripheral neuropathy, the combined treatment of mecobalamin and salvia miltiorrhiza ligustrazine has better curative effect and low incidence rate of adverse reaction, with good clinical application value. Key words: Mecobalamin; Salvia miltiorrhiza ligustrazine; Diabetic peripheral neuropathy; Sensory nerve conduction velocity (SNCV); Motor nerve conduction velocity (MNCV)