The Utilization of Leaves Extract and Senggani Fruit (Melastoma candidum D. Don) as an Interester of Bacterial Growth

Abstract

Senggani is a plant from the Melastomataceae family and the genus Melastoma. This study aims to determine the effect and the best concentration of Senggani ( Melastoma candidum D. Don) leaf and fruit extracts to suppress the growth of Escherichia coli and Staphylococcus aureus . The research design refers to the experimental research design. The independent variable (X) is Senggani leaf and fruit extract with a concentration of 1%, 5% and 10%, the total treatment in this study was 6 treatments so that the total treatment of the tested bacteria was 36 experimental units. The dependent variable (Y) is the inhibition of bacterial growth. The research method used a completely randomized design. The data analysis technique used was descriptive analysis and analysis of variance at the 95% confidence level and the LSD further test at the 95% confidence level. The results of the study concluded that (1) there was a significant effect on the concentration of Senggani ( Melastoma candidum D. Don) leaf and fruit extract as a growth inhibitor for Escherichia coli and Staphylococcus aureus (2) Senggani ( Melastoma candidum D. Don) leaf extract with a concentration of 10% was the best treatment to inhibit the growth of Escherichia coli and Staphylococcus aureus (3) The highest average diameter of the inhibition zone in E. coli given Senggani ( Melastoma candidum D. Don) leaf extract with a concentration of 10% was 11.17 mm (4) The highest average diameter of the zone of inhibition in Staphylococcus aureus given Senggani ( Melastoma candidum D. Don) leaf extract with a concentration of 10% was 10.16 mm. Keywords: Senggani, Melastoma candidum D. Don, Antibacterial Activity