THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN: SECOND REPORT

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Article1 February 1946THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN: SECOND REPORTMARTIN HENRY DAWSON, M.D., THOMAS H. HUNTER, M.D.MARTIN HENRY DAWSON, M.D.Search for more papers by this author, THOMAS H. HUNTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-2-170 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn a recent communication1the authors reported on the use of penicillin in the treatment of subacute bacterial endocarditis. Of 20 patients in whom the infecting agent was a streptococcus sensitive to the action of the drug, 15 apparently recovered; two were rendered free of infection as long as therapy was continued but subsequently relapsed; three succumbed. In the majority of cases, heparin was employed as an adjuvant to penicillin, but it was felt that further experience was necessary before an opinion could be expressed as to the value of this form of anticoagulant therapy. It was also realized that...Bibliography1. DAWSONHUNTER MHTH: The treatment of subacute bacterial endocarditis, Jr. Am. Med. Assoc., 1945, cxxvii, 129. CrossrefGoogle Scholar2. MACQUIGG R: In press. Google Scholar3. LOEWE L: The combined use of penicillin and heparin in the treatment of subacute bacterial endocarditis, Canad. Med. Assoc. Jr., 1945, lii, 1. Google Scholar4. HOBBYMEYERCHAFFEE GLKE: Activity of penicillin in vitro, Proc. Soc. Exper. Biol. and Med., 1942, l, 277. DAWSON, M. H., HOBBY, G. L., MEYER, K., CHAFFEE, E.: Penicillin as a chemotherapeutic agent, Ann. Int. Med., 1943, xix, 707. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication November 23, 1945.From the Edward Daniels Faulkner Arthritis Clinic of the Presbyterian Hospital and the Department of Medicine, Columbia University, College of Physicians and Surgeons, New York.The penicillin was provided in part by the Office of Scientific Research and Development from supplies assigned by the Committee on Medical Research for clinical investigations recommended by the Committee on Chemotherapeutics and Other Agents of the National Research Council, and in part by Mr. John L. Smith, President of Chas. Pfizer & Company, Brooklyn, N. Y.†Died April 27, 1945. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLes endocardites aiguës infectieuses sévères à travers l’histoireAntimicrobial treatment of infective endocarditis caused by viridans streptococci highly susceptible to penicillin: historic overview and future considerationsTherapie der EndokarditisErkrankungen des EndokardContinuous intramuscular-drip penicillin therapy in bacterial endocarditisTreatment of Bacterial EndocarditisEnterococcal Endocarditis as a Complication of Urologic InstrumentationBacterial endocarditisThe Lewis A. Conner Lecture of the American Heart AssociationLong-Term Follow-up Study of Penicillin-Treated Subacute Bacterial EndocarditisTHE TREATMENT OF BACTERIAL ENDOCARDITIS*EDWARD S. ORGAIN, M.D., F.A.C.P., CHARLES K. DONEGAN, M.D.The Effect of Subacute Bacterial Endocarditis on the Course of the Underlying Heart DiseasePenicillin-resistant non-hemolytic streptococcal subacute bacterial endocarditisProlonged administration of penicillin in arthritisExperiences in the management of subacute bacterial endocarditis treated with penicillinPresent status of the problem of thromboembolismTreatment of subacute bacterial endocarditis due to organisms highly resistant to penicillinRecent Developments in the Use of the Antibiotic DrugsPENICILLIN TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITISThe use of penicillin in the treatment of subacute bacterial endocarditis in childrenThe treatment of subacute bacterial endocarditis with antibiotics 1 February 1946Volume 24, Issue 2Page: 170-185KeywordsArthritisChemotherapeutic agentsDrug therapyEndocarditisHeparinHospital medicinePenicillinStreptococcal infectionsStreptococcusSurgeons ePublished: 1 December 2008 Issue Published: 1 February 1946 PDF downloadLoading ...