HEALED SUBACUTE BACTERIAL ENDOCARDITIS: REPORT OF TWO CASES WITH DEATH DUE TO CONGESTIVE HEART FAILURE

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Article1 May 1947HEALED SUBACUTE BACTERIAL ENDOCARDITIS: REPORT OF TWO CASES WITH DEATH DUE TO CONGESTIVE HEART FAILUREALVIN H. HONIGMAN, M.D., JAMES R. KARNS, M.D.ALVIN H. HONIGMAN, M.D.Search for more papers by this author, JAMES R. KARNS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-5-704 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEven though reported clinical cures of subacute bacterial endocarditis have become more frequent, there is still a remarkable paucity of pathologic confirmation of healed subacute endocarditis.Before the advent of penicillin, Weiss and Rhodes,1Libman,2and Hamman3reported autopsied cases in which the heart lesions gave evidence of complete healing. Since penicillin has been added to the armamentarium there have been increasing opportunities to study cardiac specimens of patients dying after apparently successful treatment. A very high percentage of these patients had succumbed as a result of cardiac complications. In this group Rosenblatt and Loewe4included two of their cases...Bibliography1. WEISSRHODES SCP: Healing and healed vegetative (subacute bacterial) endocarditis, New England Jr. Med., 1928, cxcix, 70-74. CrossrefGoogle Scholar2. LIBMAN E: A further report on recovery and recurrence in subacute bacterial endocarditis, Trans. Assoc. Am. Phys., 1933, xlviii, 44. Google Scholar3. HAMMAN L: Healed bacterial endocarditis, Ann. Int. Med., 1937, xi, 175-194. LinkGoogle Scholar4. ROSENBLATTLOEWE PL: Healed subacute bacterial endocarditis, Arch. Int. Med., 1945, lxxvi, 1-10. CrossrefGoogle Scholar5. MOKOTOFFBRAMSKATZHOWELL RWLNKM: The treatment of bacterial endocarditis with penicillin, Am. Jr. Med. Sci., 1946, ccxi, 395-416. CrossrefGoogle Scholar6. DAWSONHUNTER MHTH: The treatment of subacute bacterial endocarditis with penicillin, Jr. Am. Med. Assoc., 1945, cxxvii, 129-137. CrossrefGoogle Scholar7. DOLPHINCRUICKSHANK AR: Penicillin therapy in acute bacterial endocarditis, Brit. Med. Jr., 1945, i, 897-901. CrossrefGoogle Scholar8. BLOOMFIELDARMSTRONGKIRBY ALCDWM: The treatment of subacute bacterial endocarditis with penicillin, Jr. Clin. Invest., 1945, xxiv, 251-267. CrossrefGoogle Scholar9. FLIPPINMAYOCKMURPHYWOLFERTH HFRLFDCC: Penicillin in the treatment of subacute bacterial endocarditis, Jr. Am. Med. Assoc., 1945, cxxix, 841-843. CrossrefGoogle Scholar10. DAWSONHUNTER MHTH: The treatment of subacute bacterial endocarditis with penicillin. A second report, Ann. Int. Med., 1946, xxiv, 170-185. Google Scholar11. FAVOURJANEWAYGIBSONLEVINE CBCAJGSA: Progress in the treatment of subacute bacterial endocarditis, New England Jr. Med., 1946, ccxxxiv, 71-77. CrossrefGoogle Scholar12. GLASERSMITHHARFORDWOOD RJROCGWB: The treatment of bacterial endocarditis with penicillin, Jr. Lab. and Clin. Med., 1946, xxxi, 291-312. Google Scholar13. WARDMEANOCKSELBIESIMON GERIFRRD: Treatment of subacute bacterial endocarditis by penicillin, Brit. Med. Jr., 1946, i, 383-386. CrossrefGoogle Scholar14. WHITEMATHEWSEVANS PDMWE: Treatment of subacute bacterial endocarditis, Ann. Int. Med., 1945, xxii, 61-74. Google Scholar15. BLOOMFIELDHALPERN ALRM: The penicillin treatment of subacute bacterial endocarditis, Jr. Am. Med. Assoc., 1945, cxxix, 1135-1141. CrossrefGoogle Scholar16. Conference on Therapy, New York State Jr. Med., 1945, xlv, 1452-1459. Google Scholar17. WHITE PD: Heart disease, 1944, Macmillan Company, New York. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication October 1, 1946.From the Department of Medicine, University of Maryland School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySudden, Severe Aortic InsufficiencyAortic Valve Perforation in Bacterial EndocarditisDie Herz- und GefäßkrankheitenHematoma of the interatrial septumBACTERIAL ENDOCARDITIS: CLINICO-PATHOLOGIC STUDIES OF UNTREATED, TREATED AND CURED PATIENTS*HOWARD L. CORRELL, M.D., F.A.C.P., JOSEPH M. LUBITZ, M.D., F.A.C.P., M. C. F. LINDERT, M.D., F.A.C.P.The Lewis A. Conner Lecture of the American Heart AssociationThe Effect of Subacute Bacterial Endocarditis on the Course of the Underlying Heart Disease 1 May 1947Volume 26, Issue 5Page: 704-712KeywordsEndocarditisHeartHeart failureLesionsPenicillinSpecimen preparation and treatment ePublished: 1 December 2008 Issue Published: 1 May 1947 PDF downloadLoading ...