Abstract
Objective To optimize antiarrhythmic drugs in the treatment of atrial fibrillation and atrial flutter patient different duration,improve the success rate and safety of cardioversion.Methods Make a retrospective analysis of 180 atrial flutter and 180 atrial fibrillation patients data,which were divided into group ibutilide,propafenone group and amiodarone group,Each group were further divided into duration ≤ 3d > 3d,n =30,cardioversion rate was compared after 1.5h,and aralyzed by SPSS16.0.Results Atrial flutter cardioversion rate of ibutilide group ≤3d and 3d was 90% and 83.33% ;propafenone≤3d and 3d were 76.67% and 36.67%,amineamiodarone were 73.33% and 33.33%,cardioversion rate of three groups had no significant difference when atrial flutter duration ≤3d,P > 0.05 ;Ibutilide cardioversion was significantly higher than propafenone,amiodarone when atrial flutter duration > 3d,P <0.05 ;atrial fibrillation cardioversion rate of ibutilide group≤3d and 3d was 80% and 73.33% ;propafenone≤3d and 3d were 43.33% and 26.67%,amineamiodarone were 50% and 36.67%,Ibutilide cardioversion was significantly higher than propafenone,amiodarone when atrial flutter duration ≤3d,P < 0.05; Ibutilide cardioversion was significantly higher than propafenone,amiodarone when atrial flutter duration > 3d,P <0.05 ;the atrial flutter,atrial fibrillation total cardioversion rate of three groups were 81.67%,45.83%,48.33%,ibutilide was significantly higher than propafenone,amiodarone (P < 0.05 ) ;the atrial fluttercardioversion of ibutilide was significantly higher than the atrial fibrillation rate( P < 0.05 ).Conclusion For the duration of ≤ 3d patients,atrial flutter cardioversion rate of ibutilide.oropafenone,and amiodarone did not differ significantly,but the atrial fibrillation cardioversion rate of ibutilide was significantly higher;For the duration of> 3d patients,the atrial flutter and atrial fibrillation cardioversion rate of Ibutilide were higher than propafenone and amiodarone,when choose ibutilide,propafenone,or amiodarone for treating atrial flutter and atrial fibrillation according to individual arrhythmia. Key words: Atrial fibrillation ; Atrial flutter; Lbutilide; Propafenone; Amiodarone
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