Abstract
目的 评价无创血液动力学监测系统(Bioz.com)对急性心力衰竭(AHF)患者进行实时连续性血液动力学参数监测并指导AHF治疗的可行性.方法对35例AHF患者(治疗组)采用自身前后对照方法,在使用速尿或硝酸甘油前后采用Bioz.com系统实时连续监测心衰患者的心率(HR)、平均动脉压(MAP)、心排血量(CO)、加速度指数(ACI)、胸腔体液指数(TFC)、左室做功指数(LCWI)、外周血管阻力(SVR)的变化并对参数的变化进行比较;同时与健康体检人员(健康组)进行比较;并与使用Bioz.com系统进行监测前的AHF患者(对照组)4周死亡率进行比较.结果35例AHF患者,注入速尿或硝酸甘油后能快速增加CO、ACI、LCWI(P＜0.01),明显降低TFC、SVR(P＜0.01).与健康组各血液动力学参数进行比较,HR、MAP、CO、ACI、LCWI、TFC、SVR均有统计学差异(P＜0.05～0.01).4周死亡率治疗组与对照组分别为9/35(25.7%)、13/36(36.1%)(P＜0.01).结论Bioz.com系统在AHF患者中通过监测相关参数变化,为临床治疗和改善预后提供准确可靠依据,值得推广。
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