The Study of Blood Vessels of Submandibular Gland and Urinary Bladder in Rats Using an Original Morphometric Analysis

Abstract

The objective of the study is to elucidate the factors influencing treatment compliance of asthmatic patients and to introduce the measures which will facilitate rise of the compliance indices.Materials and methods. There were examined 104 patients from 18-50 years old. For the study management there were formed two groups with main one comprising 51 patients undergoing combined basic medication and allergen specific immunotherapy. The second, control group, included 53 patients who refused to undergo allergen specific immunotherapy and they received only basic medication-assisted treatment. The follow-up of the patients was conducted during a year. To determinate treatment compliance there was used own questionnaire and the control of treatment efficacy was done on the grounds of Asthma Control Test and Patient Quality of Life Questionnaire.Findings of the study and their discussion. At the beginning of the study the medium index of the patients’ treatment compliance was low in both groups. During each doctor’s visiting there were checked and worked out patients’ practical skills on accurate drug administration and control over treatment handling as well as conducting of monitoring and modification of triggers (the need in smoking cessation, active motion and bodily exercises performance, hypoallergic diet abiding, etc. was explained) and comorbidity treatment. Within three months the indices increased in both groups and some increase remained six and even twelve months after. Improvement in patients’ indices of treatment compliance was accompanied by the better performance of treatment control and quality of life. During the study the majority of patients of the main group managed to reduce a daily dose of inhaled corticosteroids and long-acting b2-agonists.Conclusion. The conducted study shows that after 12 months the indices of patients’ treatment compliance, ability to control asthma and quality of life increased in both groups while the triggers were decreased (by means of smoking cessation, comorbidity management and accommodation ecological factors control). At the same time, better results (bronchial asthma manageability, basic treatment volume decrease) were received in the group of patients with allergen-specific immunotherapy treatment application.