The effect of sublingual immunotherapy on the control level of bronchial asthma

Abstract

Allergic asthma and allergic rhinitis some of the most common forms of atopic diseases. Despite the wide range of pharmaceutical products for the treatment of allergic diseases, the main point of their application remains symptomatic treatment. Allergen-specific immunotherapy to date remains the only method of pathogenic effects on the course of allergic diseases. The aim of our work was to evaluate the effects of sublingual formulations for allergen-specific therapy on the level of control and quality of life of patients suffering from allergic form of bronchial asthma and proven sensitization to pollens of trees. The study involved 37 patients who had been previously examined by carrying out skin prick tests with allergens to detect sensitization to pollen of birch, alder and hazel. Evaluated the following parameters: the results of ACT (Asthma Control Test) test, ACQ-5 (Asthma Control Questionary) test parameters were evaluated quality of life using the SF-36 questionnaire (The Short Form 36), and spirometry. Carrying sublingual immunotherapy significantly improved the quality of life of patients and increase the performance of control of their disease.