The study of associativity with renal function and serum creatinine、serum urea nitrogen in different age stages of the chronic kidney disease patients

Abstract

Objective The patients with chronic kidney disease(CKD)were grouped by age,to con-clude the sensibility of the serum creatinine(CREA) and serum urea nitrogen(BUN) in evaluating the CKD pa-tients' renal function. Methods Using statistical treatment the associativity of the date in different age stages can be carried out,and through professional discussion the sensibility of the CREA and BUN can gained in eval-uating the CKD patients' renal function. Then it can be a direct which use the CREA and BUN to evaluate the CKD patients' renal function in different age stages in clinic. Results There are negative correlation between GFR,CREA and BUN(P <0.01 ). The absolute value of rBUN is smaller than the absolute value of rCREA. Through the grouping analyze, the same resuh to all of patients can be acquired. But in the stage of age ≥ 70 years old,the absolute value of rCBEA is smaller than the absolute value of rBUN. Conclusion In clinic job, when the CKD patients' renal function is evaluated by CBEA and BUN,it should be allowed for that the age may influence the sensibility of CREA and BUN,in the stages of age ≤ 70 years old,the sensibility of CBEA may be better than the BUN,and in the stages of age ≥ 70 years old,the sensibility of BUN may be better than the CBEA. Key words: Chronic kidney disease ( CKD ) ; Glomeralar titration rate ( GFR ) ; Serum creatinine(CREA) ; Blood urea nitrogen