Abstract

The roots of bioinformatics in protein evolution.

Highlights

  • Bioinformatics as a formal discipline came of age in the late 1980s, greatly stimulated by the 1989 Human Genome Initiative

  • Many other authors have already recorded their thoughts on the evolutionary roots of bioinformatics in accounts that are doubtless more thorough and balanced than can be recorded in this brief personal reflection ([1,2], inter alia)

  • All are in agreement about certain pivotal events that were true milestones: the double-helix model of DNA, the first determination of the amino acid sequence of a protein, and the conceptual linking of DNA sequences and protein sequences

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Summary

Introduction

Bioinformatics as a formal discipline came of age in the late 1980s, greatly stimulated by the 1989 Human Genome Initiative. The first step in determining the sequence of a peptide or protein was to establish its amino acid composition.

Results
Conclusion
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