Abstract
Abstract The applications anticipated for nuclear magnetic resonance (NMR) in pharmaceutical analysis include the identification of compounds, elucidation of unknown structures, determination of sample purity, and quantitative analysis. “Fingerprint” identification of a sample is often readily possible with the aid of spectra catalogs. Examples are shown of how NMR aided in the structure elucidation of several compounds, particularly that of anthralin. Only in certain cases can NMR sensitively detect impurities; the necessary conditions and limitations for such detection are discussed. Comparisons are made of the ease with which impurities in selected phenothiazine drugs were detected by IR and NMR. Two different methods for quantitatively determining the relative amounts of components in a mixture are discussed. Future avenues of collaborative studies are indicated.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
