The Role of Herbal Medicine in Oxidative Stress: Prevention of Diabetes

Abstract

The pathophysiology of diabetes mellitus is heavily influenced by oxidative stress, which is defined by an imbalance between reactive oxygen species (ROS) and antioxidant defenses. Innovative methods for managing and preventing diabetes are required given that it is a growing worldwide health concern. Herbal medicine, which has a long history of use in traditional therapeutic methods, has drawn interest for its ability to reduce the incidence of diabetes and combat oxidative stress. The processes underpinning the damage caused by ROS to cellular components and signaling pathways are revealed in this chapter as it delves into the complex interactions between oxidative stress and diabetes. The essential function of antioxidant substances in reducing oxidative stress is investigated, emphasizing the change from traditional herbal knowledge to contemporary scientific validation. The botanical substances that provide a source of inorganic antioxidants are at the center of this discussion. Fenugreek (Trigonella foenum-graecum) and Bitter Melon (Momordica charantia), two important medicinal herbs, are investigated for their strong antioxidant capacities and their capacity to modify glucose homeostasis and insulin sensitivity.Scientific studies, including in vitro experiments and clinical trials, shed light on how well herbal treatments for diabetes prevention actually work. Additionally, the beneficial effects of herbal combinations are clarified, as well as the importance of combining these interventions with lifestyle changes. The fusion of herbal medicine and conventional therapies appears as a promising route for diabetes prevention as the movement toward holistic health gains popularity. In conclusion, this chapter underscores the multifaceted potential of herbal medicine in addressing oxidative stress as a crucial factor in diabetes prevention. By embracing the wisdom of ancient traditions and leveraging contemporary scientific insights, herbal interventions offer a holistic and integrative strategy to safeguard against the escalating global burden of diabetes.