The relationship of pancreatic fat content and lipid levels in individuals with newly diagnosed type 2 diabetes

Abstract

Objective To investigate association of pancreatic fat content and lipid levels in individuals with newly diagnosed type 2 diabetes. Methods Fifty four subjects with newly diagnosed type 2 diabetes and 22 volunteers without type 2 diabetes were enrolled in this study. Pancreatic fat content was determined with magnetic resonance imaging. Lipid levels were measured. Results The pancreatic fat content in patients with newly diagnosed type 2 diabetes and control subjects was (17.13±10.35)% and (11.62±7.15)%, respectively (P=0.025). Median pancreatic fat content of subjects with newly diagnosed type 2 diabetes correlated negatively with total cholesterol level (r=-0.361, P=0.007) and triglycerides level (r=-0.346, P=0.010). Conclusions Increased levels of serum total cholesterol and low density lipoprotein cholesterol might relieve the extent of pancreatic fat content. Key words: Diabetes mellitus, type 2/ME; Pancreas/ME; Fats/ME; Lipids