Abstract
目的 探讨MMP-9、TIMP-1、MMP-2、TIMP-2表达与胃肠道间质瘤(GIST)生物学行为的关系,为预测该肿瘤的侵袭潜能提供理论依据和可能的预测指标,以指导临床的治疗和预后.方法对70例GIST利用组织微阵列技术制片进行免疫组织化学染色,并结合病理形态学及生物学行为评价进行统计学分析.结果(1)MMP-9的表达率为65/69(94.2%),MMP-9的阳性表达程度与GIST的生物学行为有显著相关性;MMP-2、TIMP-1、TIMP-2的表达率分别为47.8%、98.6%和95.7%.结论MMP-9表达与GIST生物学行为关系密切,可作为GIST生物学行为的潜在评价指标。
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
