The relationship between lymphatic metastasis and tumor volume in patients with non small cell lung cancer

Abstract

Objective To discuss the relationship between the incidence of lymph node metastasis and tumor size in patients with non small cell lung cancer, and to provide evidence for clinical operation and follow-up treatment. Methods 180 patients with non small cell lung cancer who were hospitalized and recieived Lobectomy operation were selected, the clinical data of patients and resection of tumor size, lymph node metastasis were retrospectively analyzed, and then the relationship between the lymph node metastasis and tumor volume was investigated. Results 180 cases of patients with lymph node metastasis rate was 37.20%, in which hilar lymph node metastasis rate was 11.02 percent and mediastinal lymph node metastasis rate was 10.95%.Lung lymph node metastasis rates in lymph node metastasis, hilar and mediastinal lymph node metastasis of T1a were 13.21%, 15.09% and 13.21%; those of T1b period were 38.09%, 35.71% and 28.57%; of T2a period were 44.44%, 37.78% and 31.11%; of T2b period were 64.26%, 57.14% and 53.57%; and those of T3 period were 58.33%, 66.67% and41.67%.Lymph node metastasis, hilar and mediastinal lymph node metastasis in lung lymph nodes transfer rate with patients of T1a had significantly differences compared with patients of T1b, T2a, T2b and T3 stage.(χ2=5.363, 6.175, 4.372, 8.778, 5.363, 9.631, 7.936, 9.631, 20.463, 7.521, 6.175, 4.387, all P<0.05). Hilar lymph node metastasis and lung metastases of T1b and T2b had a significant difference (χ2=12.353, 4.585, all P<0.05). Conclusion For non-small cell lung cancer, tumor size is positively correlated with lymph node metastasis and the greater the tumor size, the greater the likelihood of lymph node metastasis. Key words: Tumor volume; Tumor metastasis; Lymph nodes; Carcinoma, non small cell lung