The relationship between endometrial thickness and pregnancy rates in subfertil women underwent intrauterine insemination Following ovulation induction

Abstract

Objective: The aim of this study is the comparison of effects of Clomiphene Citrate (CC) & human menopausal Gonadotrophin (hMG) stimulated cycles on the Endometrial Thickness (ET) in intrauterine insemination (IUI) in one cycle & to establish any relation between ET on the day of IUI and achieving clinical pregnancy in these stimulated cycle.Study design: A prospective observational study was undertaken for assessing effects of clomiphene citrate (CC) and human menopausal gonadotrophin hMG stimulated cycle on the ET and clinical pregnancy in single IUI cycle.Subfertility cases were studied in two groups; Group A [ovulation induction (OI) with CC and IUI, n = 150] and Group B (OI with hMG and IUI, n = 150).Results: Comparable data obtained in mean, age, duration of subfertility female, male (only oligo sperm a) in both group range of ET of clinical pregnancy in group A (n = 21) were 8.0 – 12.9 mm and 9.0 – 12.9 mm in group B (n = 40). (p value < 0.001) ongoing pregnancy beyond 1st trimester was higher in group B (n= 42) than group A (n = 19).Conclusion: Mean ET and clinical pregnancy rate both were higher in hMG group compared to CC.