Abstract

Background: Multiple sclerosis (MS) is an autoimmune disease characterized by the demyelination of axons in the central nervous system (CNS). Urinary tract infection (UTI) affects millions of people each year. UTI is a common risk factor that worsens attacks in patients with MS. Aims: The commonest pseudo exacerbations in patients with MS is UTI, in addition to the influence of UTI on disease activity and development; therefore, the research aims to study the prevalence of urinary tract Methods: The current study included sixty MS patients aged 15-57 years from May 2023 to March 2024 in MS clinic at Imam Al- Hussein medical city in Kerbala, Saad Al-Witry Hospital for Neuroscience in Baghdad and MS clinic at Middle Euphrates center for Neuroscience in Najaf. Ten ml of urine samples were collected from MS patients, and a general urine examination (GUE) was done. The urine sample was inoculated into the culture media, after which VITEK diagnosed it. Results: The UTI prevalence in patients with MS was about 23%; E. coli was the most frequent, while other bacteria were less frequent, ranging between (15-7%). Discussion: UTI infection is a risk factor in autoimmune diseases. Conclusions: Multiple sclerosis patients are likely to have UTI. They are community- and hospital-acquired, especially because of E. coli. In addition to autoimmune diseases, it is a risk of systemic infections.

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