The present status of hyperuricemia in civil aviation flying personnel

Abstract

Objective To investigate the relationship between the level of blood uric acid and blood fat, body mass index (BMI), waist circumference, blood pressure, fatty liver disease, diabetes, urinary calculi in flying personnel of Civil Aviation Flight University of China, to search for risk factors leading to hyperuricemia, and to discuss the normal range of blood uric acid of flying personnel and prevention measures. Methods The physical examination data of 1 721 flying personnel in Civil Aviation Flight University of China were analyzed through the retrospective analysis method. According to blood uric acid level, they were divided into two groups: hyperuricemia group and control group. The comparisons on the difference of blood fat, BMI, waist circumference, and on the prevalence of hypertension, diabetes, kidney stones, fatty liver were done between two groups. Effective factors of blood uric acid were analyzed with the non-conditional Logistic regression. Results In 1 721 examined flying personnel, prevalence rate of hyperuricemia was 25.10%. BMI and waist circumference in hyperuricemia group was respectively bigger than that of control group. The triglyceride, cholesterol and LDL-C level in hyperuricemia group was respectively higher than that of control group. HDL-C in hyperuricemia group was lower than that of control group (t=2.764-7.24, P<0.01) . The percentage of drinking and fatty liver prevalence in hyperuricemia group were higher than those in control group (χ2=5.710, 7.513, P<0.05)). Abdominal obesity, hyperlipemia and drinking habit were significantly related to hyperuricemia (P<0.05). Conclusions BMI, waist circumference, the level of blood fat, drinking habit and fatty liver are related to hyperuricemia. Abdominal obesity, hyperlipidemia and drinking habit are the main risk factors which cause hyperuricemia of civil flying personnel. The preventions such as controlling the weight and the level of blood fat, as well as banning drinking would be helpful to manage the level of blood uric acid. The necessary therapy of uric acid restraining is also suggested. Key words: Hyperuricemia; Risk factors; Epidemiologic studies; Aircrews