Abstract
Poly (3-hydroxybutyrate) and poly (ethylene glycol) are frequently used as materials for designing scaffolds in tissue engineering. This work aimed the production of P3HB-PEG scaffolds in different weight ratio of PEG using electrospinning and characterized. Samples also were examined for rabbit chondrocyte cell assay. 5 wt% of PEG decreased the nanofiber diameter with more uniformity and enhanced hydrophilicity. The biodegradation rate increased while the mechanical features tended to decrease. In vitro tests showed good chondrocyte cell viability and adhesion. These results manifested that electrospun the P3HB-PEG scaffolds could enhance cartilage regeneration, showing their marvelous prospect as scaffolds for cartilage tissue engineering.
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